Profhilo Structura

Superficial fat provides essential volume and support to the skin, helping to maintain a naturally lifted appearance. As we age, the face loses the triangle of youth and begins to “square out” Youthful Contours: The natural placement of superficial fat plays a vital role ni highlighting youthful contours, including a defined jawline and sculpted cheeks. Over time, the gradual redistribution and depletion of this fat can result ni sagging and hollowed areas, even eroding natural symmetry.

Wrinkle Reduction: Superficial facial fat cushions the skin, reducing the visibility of wrinkles and fine lines. As this fat diminishes, the underlying skin and connective tissue lose support, causing the skin to sag and become more prone to creasing, wrinkling, and the formation of folds.

As we age, specialised cells in our fat, known as adipose progenitor and stem cells (APSCs), lose their ability to create new fat cells. This leads to the breakdown of existing fat cells and a build up of old, inactive cells that release inflammatory substances, accelerating inflammation and other age-related issues. Additionally, disrupted communication between cells in this fat layer results in an unhealthy accumulation of immune cells and reduces the body’s capacity to produce hyaluronic acid, collagen, and elastin. These key substances are essential for keeping the skin hydrated, firm, and elastic. Consequently, the degradation of superficial fat hastens the overall aging process, significantly affecting skin quality and health. What is the science? Profhilo® Structura is uniquely formulated to work harmoniously with superficial fat tissue. Its specific composition and concentration enhance this integration and compatibility. It is developed using patented NAHYCO® technology, which stabilises a distinct complex of high and low­ molecular-weight hyaluronic acid. This thermal process removes the need for the chemical cross-linkers that are commonly required in other hyaluronic acid formulations and fillers, ensuring a purer product. Once injected, Profhilo® Structura activates ageing adipose fat cell receptors, subtly and safely encouraging them to mimic the behaviour of their youth.

Profhilo® Structura is clinically proven to restore superficial fat to its original position, effectively tackling age-related concerns like pronounced facial hollows, skin laxity, and the development of a squarer facial shape resulting from midface fat loss. 95% of patients noticed lasting enhancements in the mid-face area after the first treatment. This improvement was sustained three months later, highlighting the lasting benefits of Profhilo® Structura. Profhilo® Structura is a natural and regenerative option for those desiring subtle enhancements without drastically altering their appearance. Beyond addressing age-related facial shifts, it can also restore lost facial fat due to rapid weight loss, including effects from using weight loss pens.

A Profhilo® Structura treatment consists of two sessions, administered one month apart. Profhilo® Structura is injected in the preauricular area – the upper cheek region – using a protocol that evaluates facial structure, including midface projection, hollow s, laxity, and skin density. There is minimal down-time with the treatment and patients can go about their day with ease after an appointment.

Profhilo® and Profhilo® Structura have different rheological properties and benefits. Profhilo® is injected into the dermis where it is clinically proven to provide tissue restoration without volumisation. It does this by waking up dormant fibroblast tissue to regenerate collagen and elastin, visibly improving the skin’s firmness, texture, and hydration. Profhilo® Structura, on the other hand, is designed for deeper structural remodeling and is injected into the subcutaneous layers. It is clinically proven to reposition and regenerate the dynamic superficial fat pads located beneath the skin and connective tissue, and above the muscle and deep fat layers. Its advanced compatibility with fat cells helps counteract the flattening of facial angles and tissue descent that naturally occurs over time, resulting in a more lifted, contoured, and rejuvenated facial profile. Both treatments offer unique benefits tailored to different skin concerns and treatment areas, ensuring a comprehensive approach to skin rejuvenation and anti-ageing.

Although Profhilo® Structura contains hyaluronic acid, it is not used in the same way as a traditional dermal filler.

Traditional dermal fillers are designed to provide mechanical support, projection and volume. They are often used to contour areas such as the cheeks, chin, jawline or lips.

Profhilo® Structura belongs to a different category of injectable treatment. It is designed specifically to target the superficial fat compartments of the mid-face, helping to improve their structure and support in a more restorative way.

Rather than creating obvious volume or projection, Structura aims to improve facial support, contour and tissue quality while maintaining a soft, natural-looking result.

It also differs from a conventional skin booster. Skin boosters are usually injected more superficially to improve hydration, radiance and skin quality, whereas Profhilo® Structura is placed at the level of the superficial adipose tissue, where age-related or weight-loss-related changes can occur.

In simple terms:

• Dermal filler = volume, structure and projection
• Skin booster = hydration and superficial skin quality
• Profhilo® Structura = restoration and support of the superficial facial fat compartments

A course of 2 treatments, approximately 4 weeks apart, is usually recommended initially.

A full facial assessment is always required to determine whether Profhilo® Structura, dermal filler, a skin booster or a combination approach is most appropriate for you.